Unlocking the Power of Polynucleotides for Advanced Skin Regeneration Techniques
- aga929

- Sep 10
- 3 min read
At NOVA Wellness Clinic, we’re passionate about staying at the forefront of aesthetic innovation — offering treatments that are backed by science and deliver real, regenerative results. One of the most exciting new developments in regenerative aesthetics is Polynucleotide therapy – a powerful, biostimulatory treatment that is transforming the way we care for skin ageing, acne scarring, and skin laxity.
If you’re looking for a natural, non-surgical way to restore your skin’s vitality, improve texture, and boost hydration from within, Polynucleotides may be the treatment for you.

What Are Polynucleotides?
Polynucleotides are fragments of DNA derived from purified salmon DNA (completely biocompatible with the human body) that work to stimulate your skin's natural regeneration processes. Unlike dermal fillers, which simply add volume, polynucleotides encourage your own cells to repair, renew and rebuild.
They are injected into targeted areas of the skin, where they:
Stimulate fibroblast activity (which boosts collagen and elastin production)
Promote deep hydration
Encourage tissue regeneration
Improve microcirculation and skin quality
This treatment is often described as “injectable skin healing” — ideal for tired, dull, scarred or ageing skin that needs a biological reset.
What Is Polynucleotide Treatment Used For?
Polynucleotide therapy is incredibly versatile and suitable for both men and women seeking a natural, regenerative approach to skin ageing and repair. It can be used on the face, neck, décolletage, under-eye area, and even hands or scalp.
Common concerns it treats include:
Fine lines and wrinkles
Crepey or sagging skin
Acne scarring
Dark under-eye circles and skin thinning
Dull, dehydrated or tired-looking skin
Loss of elasticity or tone
It’s also being used in hair restoration protocols, where it can support scalp health and stimulate follicle activity.
Is There Downtime?
One of the advantages of polynucleotide treatment is that it involves minimal downtime. After treatment, you may experience:
Mild redness or swelling at the injection points
Occasional small bruises
Slight tenderness for 24–48 hours
These are temporary and usually resolve quickly. Most people return to daily activities the same day, with no need to take time off.
Who Should Avoid Polynucleotides?
While polynucleotide treatments are safe for most people, there are a few contraindications:
Pregnancy or breastfeeding
Active skin infections or inflammation in the treatment area
Autoimmune conditions affecting skin healing
Allergy to fish or seafood (as the polynucleotides are salmon-derived)
As always, we carry out a thorough consultation and medical assessment prior to treatment to ensure it’s right for you.
What Results Can I Expect?
Polynucleotides work gradually, as they stimulate your skin’s natural repair processes. You won’t see instant changes like with fillers — but the improvements are real, progressive and long-lasting.
Most clients begin to notice:
Improved skin texture and radiance
Smoother, firmer skin
Reduction in fine lines
Healthier, more hydrated complexion
More even skin tone
We usually recommend a course of 2–4 treatments spaced 2–4 weeks apart for optimal results, with maintenance sessions every 4–6 months depending on your skin goals.
A Regenerative Future for Skin Health
Polynucleotide therapy represents a new era in aesthetic medicine — one focused on regeneration, repair, and long-term skin health, rather than just surface-level fixes. At NOVA Wellness Clinic, we’re proud to offer this treatment as part of our commitment to natural, science-led skin rejuvenation.
Book a Consultation
If you’d like to find out whether polynucleotide therapy is right for you, we invite you to book a personal consultation. We’ll assess your skin, talk through your goals, and create a bespoke plan tailored to you. Please email us here at hello@nova-wellenss.o.uk
Heal. Rebuild. Glow – naturally.



